:root {
    --ink: #152321;
    --muted: #60706c;
    --paper: #f4f1e8;
    --card: #fffdf8;
    --deep: #102e2b;
    --deep-2: #173d39;
    --line: #d9ded8;
    --lime: #b8ef72;
    --lime-dark: #49751f;
    --copper: #c86f4a;
    --blue: #4c7f86;
    --amber: #d6a343;
    --red: #a54a42;
    --shadow: 0 20px 55px rgba(25, 47, 43, 0.09);
    --radius: 22px;
    --radius-sm: 13px;
    --shell: 1180px;
}

* { box-sizing: border-box; }
html { scroll-behavior: smooth; }
body {
    margin: 0;
    background: var(--paper);
    color: var(--ink);
    font-family: Inter, ui-sans-serif, system-ui, -apple-system, BlinkMacSystemFont, "Segoe UI", sans-serif;
    font-size: 17px;
    line-height: 1.62;
    text-rendering: optimizeLegibility;
}
button, input, select { font: inherit; }
a { color: inherit; text-underline-offset: .18em; }
img { max-width: 100%; height: auto; }
.shell { width: min(calc(100% - 32px), var(--shell)); margin-inline: auto; }
.sr-only { position: absolute; width: 1px; height: 1px; padding: 0; margin: -1px; overflow: hidden; clip: rect(0,0,0,0); white-space: nowrap; border: 0; }
.skip-link { position: absolute; left: 12px; top: -60px; background: #fff; color: #000; padding: 10px 14px; z-index: 1000; }
.skip-link:focus { top: 12px; }

.site-header { background: var(--deep); color: #fff; position: sticky; top: 0; z-index: 50; border-bottom: 1px solid rgba(255,255,255,.1); }
.header-inner { min-height: 78px; display: flex; align-items: center; justify-content: space-between; gap: 24px; }
.brand { display: inline-flex; align-items: center; gap: 13px; text-decoration: none; min-width: 260px; }
.brand strong { display: block; font-size: 1rem; letter-spacing: .01em; }
.brand small { display: block; color: #b8cbc6; font-size: .72rem; margin-top: -2px; }
.brand-mark { width: 42px; height: 42px; border-radius: 50%; position: relative; border: 1px solid rgba(184,239,114,.7); display: inline-grid; place-items: center; flex: 0 0 auto; }
.brand-mark span { position: absolute; width: 6px; height: 6px; background: var(--lime); border-radius: 50%; box-shadow: 0 0 14px rgba(184,239,114,.7); }
.brand-mark span:nth-child(1) { transform: translate(-10px, 5px); }
.brand-mark span:nth-child(2) { transform: translate(10px, -6px); }
.brand-mark span:nth-child(3) { transform: translate(1px, 11px); }
.primary-nav { display: flex; align-items: center; gap: 6px; }
.primary-nav a { color: #dce9e5; text-decoration: none; padding: 9px 12px; border-radius: 9px; font-size: .92rem; }
.primary-nav a:hover, .primary-nav a.active { background: rgba(255,255,255,.09); color: #fff; }
.primary-nav a.active { box-shadow: inset 0 -2px 0 var(--lime); }
.nav-toggle { display: none; background: transparent; border: 0; padding: 8px; }
.nav-toggle span:not(.sr-only) { display: block; width: 24px; height: 2px; background: white; margin: 5px 0; }
.medical-banner { background: #e3ebdf; border-bottom: 1px solid #cbd7c7; color: #395149; font-size: .79rem; }
.medical-banner .shell { padding-block: 7px; }

.hero { background: var(--deep); color: #fff; overflow: hidden; position: relative; }
.hero::before { content: ""; position: absolute; width: 520px; height: 520px; border: 1px solid rgba(184,239,114,.13); border-radius: 50%; right: -180px; top: -210px; box-shadow: 0 0 0 75px rgba(184,239,114,.025), 0 0 0 150px rgba(184,239,114,.018); }
.hero-grid { display: grid; grid-template-columns: 1.22fr .78fr; gap: 58px; align-items: center; padding: 88px 0 82px; position: relative; }
.eyebrow { display: inline-flex; align-items: center; gap: 9px; text-transform: uppercase; letter-spacing: .13em; font-size: .74rem; font-weight: 750; color: var(--copper); margin-bottom: 16px; }
.eyebrow::before { content: ""; width: 24px; height: 2px; background: currentColor; }
.hero h1, .page-hero h1 { margin: 0; font-family: Georgia, "Times New Roman", serif; font-weight: 500; letter-spacing: -.035em; line-height: 1.04; }
.hero h1 { font-size: clamp(3rem, 6vw, 5.7rem); max-width: 850px; }
.hero h1 em { color: var(--lime); font-style: normal; }
.hero-copy { font-size: 1.15rem; max-width: 750px; color: #c9d9d5; margin: 24px 0 30px; }
.hero-actions { display: flex; flex-wrap: wrap; gap: 12px; }
.button { display: inline-flex; align-items: center; justify-content: center; gap: 8px; padding: 12px 17px; min-height: 48px; border-radius: 11px; border: 1px solid transparent; background: var(--lime); color: #173018; font-weight: 750; text-decoration: none; cursor: pointer; }
.button:hover { transform: translateY(-1px); filter: brightness(.98); }
.button.secondary { background: transparent; color: #fff; border-color: rgba(255,255,255,.3); }
.button.ghost { background: transparent; color: var(--deep); border-color: #afbbb6; }
.button.small { padding: 8px 12px; min-height: 38px; font-size: .87rem; }
.hero-panel { background: rgba(255,255,255,.06); border: 1px solid rgba(255,255,255,.12); border-radius: var(--radius); padding: 25px; backdrop-filter: blur(10px); }
.hero-panel h2 { font-size: 1rem; margin: 0 0 15px; color: #e7f1ee; }
.hero-stat { display: grid; grid-template-columns: 70px 1fr; gap: 15px; padding: 15px 0; border-top: 1px solid rgba(255,255,255,.1); }
.hero-stat:first-of-type { border-top: 0; }
.hero-stat strong { font-family: Georgia, serif; font-size: 2.1rem; color: var(--lime); line-height: 1; }
.hero-stat span { color: #c2d2ce; font-size: .88rem; }

.section { padding: 74px 0; }
.section.tight { padding: 48px 0; }
.section.dark { background: var(--deep); color: #fff; }
.section-head { display: flex; align-items: end; justify-content: space-between; gap: 30px; margin-bottom: 30px; }
.section-head h2 { margin: 0; font-family: Georgia, serif; font-size: clamp(2rem, 4vw, 3.2rem); font-weight: 500; letter-spacing: -.025em; line-height: 1.1; }
.section-head p { margin: 0; max-width: 550px; color: var(--muted); }
.dark .section-head p { color: #bed0cb; }
.kicker { color: var(--copper); text-transform: uppercase; font-weight: 800; font-size: .75rem; letter-spacing: .12em; }

.search-panel { background: var(--card); border: 1px solid var(--line); border-radius: var(--radius); padding: 22px; box-shadow: var(--shadow); margin-top: -34px; position: relative; z-index: 3; }
.search-row { display: grid; grid-template-columns: 1fr 230px auto; gap: 12px; }
.field { display: flex; flex-direction: column; gap: 7px; }
.field label { font-size: .78rem; font-weight: 800; color: #40534e; text-transform: uppercase; letter-spacing: .08em; }
.input, .select { width: 100%; min-height: 48px; border: 1px solid #bdc9c4; border-radius: 10px; background: #fff; color: var(--ink); padding: 10px 13px; }
.input:focus, .select:focus { outline: 3px solid rgba(76,127,134,.2); border-color: var(--blue); }

.card-grid { display: grid; grid-template-columns: repeat(3, minmax(0, 1fr)); gap: 18px; }
.evidence-card { background: var(--card); border: 1px solid var(--line); border-radius: 18px; padding: 23px; display: flex; flex-direction: column; min-height: 100%; transition: transform .16s ease, box-shadow .16s ease, border-color .16s ease; }
.evidence-card:hover { transform: translateY(-3px); box-shadow: var(--shadow); border-color: #b7c5bf; }
.card-top { display: flex; align-items: flex-start; justify-content: space-between; gap: 12px; margin-bottom: 18px; }
.category { font-size: .72rem; text-transform: uppercase; letter-spacing: .08em; font-weight: 800; color: var(--blue); }
.evidence-card h3 { font-family: Georgia, serif; font-weight: 500; font-size: 1.55rem; line-height: 1.14; margin: 5px 0 9px; }
.evidence-card p { color: #52625f; margin: 0 0 18px; font-size: .93rem; }
.card-footer { margin-top: auto; display: flex; justify-content: space-between; align-items: center; gap: 14px; border-top: 1px solid #e1e5e1; padding-top: 15px; }
.card-footer a { text-decoration: none; font-weight: 800; color: var(--deep); }
.card-footer a:hover { text-decoration: underline; }
.badge { display: inline-flex; align-items: center; gap: 7px; border-radius: 999px; padding: 6px 10px; font-size: .72rem; line-height: 1; font-weight: 800; white-space: nowrap; }
.level-useful { background: #def0d2; color: #365b24; }
.level-promising { background: #f1e7bd; color: #765b10; }
.level-early { background: #dcebed; color: #315d64; }
.level-indirect { background: #ece3db; color: #76503d; }
.level-none { background: #efdddd; color: #783a36; }
.level-neutral { background: #e8ece9; color: #45544f; }
.score-chip { display: inline-flex; align-items: center; gap: 6px; font-size: .74rem; color: #5f6d69; }
.score-chip::before { content: ""; width: 9px; height: 9px; border-radius: 50%; background: currentColor; }
.score-4 { color: #3b7b36; }
.score-3 { color: #648940; }
.score-2 { color: #b1842d; }
.score-1 { color: #b76b46; }
.score-0 { color: #9b5650; }

.feature-grid { display: grid; grid-template-columns: repeat(3, 1fr); gap: 20px; }
.feature-card { border-radius: var(--radius); padding: 28px; background: #fff; border: 1px solid var(--line); }
.feature-card .number { font-family: Georgia, serif; font-size: 3.3rem; color: var(--copper); line-height: 1; }
.feature-card h3 { margin: 16px 0 8px; font-size: 1.3rem; }
.feature-card p { color: var(--muted); margin: 0 0 16px; }
.feature-card a { font-weight: 800; text-decoration: none; }
.feature-card a:hover { text-decoration: underline; }

.split { display: grid; grid-template-columns: 1fr 1fr; gap: 30px; align-items: start; }
.quote-panel { padding: 34px; background: #e7e2d4; border-radius: var(--radius); border-left: 4px solid var(--copper); }
.quote-panel blockquote { margin: 0; font-family: Georgia, serif; font-size: 1.45rem; line-height: 1.35; }
.quote-panel cite { display: block; margin-top: 18px; font-style: normal; font-size: .85rem; color: #58635f; }
.clean-list { list-style: none; padding: 0; margin: 0; }
.clean-list li { position: relative; padding-left: 26px; margin: 11px 0; }
.clean-list li::before { content: ""; position: absolute; left: 0; top: .72em; width: 10px; height: 10px; border-radius: 50%; background: var(--lime-dark); box-shadow: 0 0 0 4px rgba(73,117,31,.12); }

.page-hero { background: var(--deep); color: #fff; padding: 60px 0 64px; }
.page-hero h1 { font-size: clamp(2.7rem, 5vw, 4.6rem); max-width: 880px; }
.page-hero p { max-width: 780px; color: #c6d6d2; font-size: 1.08rem; margin: 20px 0 0; }
.breadcrumbs { font-size: .8rem; color: #aabfba; margin-bottom: 17px; }
.breadcrumbs a { color: #d9e7e3; }
.page-body { padding: 58px 0 78px; }
.content-grid { display: grid; grid-template-columns: minmax(0, 1fr) 320px; gap: 42px; align-items: start; }
.prose { max-width: 800px; }
.prose h2 { font-family: Georgia, serif; font-weight: 500; font-size: 2rem; margin: 42px 0 13px; line-height: 1.15; }
.prose h3 { margin-top: 28px; }
.prose p { color: #334542; }
.prose a { color: #245f63; }
.prose ul { padding-left: 21px; }
.prose li { margin: 9px 0; }
.sidebar { position: sticky; top: 120px; display: grid; gap: 16px; }
.sidebar-card { background: var(--card); border: 1px solid var(--line); border-radius: 16px; padding: 20px; }
.sidebar-card h2, .sidebar-card h3 { margin-top: 0; font-size: 1rem; }
.sidebar-card p { margin-bottom: 0; font-size: .86rem; color: var(--muted); }
.sidebar-card a { font-weight: 750; }

.matrix { display: grid; grid-template-columns: repeat(2, minmax(0, 1fr)); gap: 12px; margin: 25px 0; }
.matrix-item { background: #fff; border: 1px solid var(--line); border-radius: 12px; padding: 15px; }
.matrix-label { display: flex; justify-content: space-between; align-items: center; gap: 12px; font-size: .82rem; font-weight: 800; }
.meter { height: 8px; background: #e7ebe7; border-radius: 99px; margin-top: 10px; overflow: hidden; }
.meter span { display: block; height: 100%; border-radius: 99px; background: currentColor; }
.source-list { display: grid; gap: 13px; }
.source-card { border: 1px solid var(--line); background: #fff; padding: 17px; border-radius: 13px; }
.source-card a { font-weight: 800; text-decoration: none; }
.source-card a:hover { text-decoration: underline; }
.source-meta { display: flex; flex-wrap: wrap; gap: 8px 13px; margin-top: 7px; font-size: .75rem; color: var(--muted); }
.source-card p { margin: 8px 0 0; font-size: .87rem; color: #52625f; }
.notice { background: #edf2e9; border: 1px solid #cfdbca; border-radius: 14px; padding: 18px; }
.notice.warning { background: #f5eadf; border-color: #e2c3a8; }
.notice strong { display: block; margin-bottom: 4px; }

.filters { display: flex; gap: 8px; flex-wrap: wrap; margin: 20px 0 26px; }
.filter-button { border: 1px solid #b7c2bd; background: #fff; border-radius: 999px; padding: 8px 12px; cursor: pointer; font-weight: 750; font-size: .82rem; }
.filter-button.active { background: var(--deep); color: #fff; border-color: var(--deep); }
.no-results { display: none; background: #fff; padding: 30px; border: 1px dashed #9eaaa5; border-radius: 15px; text-align: center; }

.trial-grid { display: grid; grid-template-columns: repeat(2, minmax(0, 1fr)); gap: 18px; }
.trial-card { background: #fff; border: 1px solid var(--line); border-radius: 17px; padding: 22px; }
.trial-card h2 { font-family: Georgia, serif; font-size: 1.45rem; font-weight: 500; margin: 12px 0 8px; line-height: 1.2; }
.trial-meta { display: flex; flex-wrap: wrap; gap: 7px; }
.trial-card p { color: var(--muted); }
.trial-links { display: flex; flex-wrap: wrap; gap: 10px; align-items: center; margin-top: 17px; }

.audit-layout { display: grid; grid-template-columns: minmax(0, 1.05fr) minmax(330px, .95fr); gap: 28px; align-items: start; }
.audit-picker { background: #fff; border: 1px solid var(--line); border-radius: var(--radius); padding: 24px; }
.audit-search { margin-bottom: 16px; }
.check-grid { display: grid; grid-template-columns: repeat(2, minmax(0, 1fr)); gap: 8px; max-height: 580px; overflow: auto; padding-right: 5px; }
.check-card { display: grid; grid-template-columns: auto 1fr auto; gap: 9px; align-items: center; border: 1px solid #d7ddd8; border-radius: 11px; padding: 11px; cursor: pointer; }
.check-card:hover { background: #f5f7f3; }
.check-card input { width: 18px; height: 18px; accent-color: var(--deep); }
.check-card small { color: var(--muted); }
.audit-results { position: sticky; top: 118px; display: grid; gap: 14px; }
.audit-summary { background: var(--deep); color: #fff; border-radius: var(--radius); padding: 23px; }
.summary-grid { display: grid; grid-template-columns: repeat(3, 1fr); gap: 10px; margin-top: 17px; }
.summary-stat { background: rgba(255,255,255,.08); border-radius: 12px; padding: 12px; }
.summary-stat strong { display: block; font-family: Georgia, serif; color: var(--lime); font-size: 1.65rem; line-height: 1; }
.summary-stat span { font-size: .72rem; color: #c6d6d2; }
.finding { background: #fff; border: 1px solid var(--line); border-left-width: 5px; border-radius: 13px; padding: 16px; }
.finding h3 { font-size: .97rem; margin: 0 0 5px; }
.finding p { font-size: .85rem; color: var(--muted); margin: 0; }
.finding-context { border-left-color: var(--blue); }
.finding-duplication { border-left-color: var(--amber); }
.finding-timing { border-left-color: #8a76b0; }
.finding-caution { border-left-color: var(--red); }
.finding-neutral { border-left-color: #82a56a; }
.empty-state { background: #fff; border: 1px dashed #aab5b0; border-radius: 14px; padding: 24px; color: var(--muted); }

.compare-form { background: #fff; border: 1px solid var(--line); border-radius: var(--radius); padding: 22px; display: grid; grid-template-columns: 1fr auto 1fr auto; align-items: end; gap: 14px; }
.compare-vs { align-self: center; font-weight: 900; color: var(--copper); padding-top: 22px; }
.compare-grid { display: grid; grid-template-columns: 1fr 1fr; gap: 20px; margin-top: 28px; }
.compare-card { background: #fff; border: 1px solid var(--line); border-radius: var(--radius); overflow: hidden; }
.compare-card header { padding: 22px; background: #ecf1eb; }
.compare-card header h2 { margin: 5px 0 8px; font-family: Georgia, serif; font-weight: 500; font-size: 2rem; }
.compare-card-body { padding: 22px; }
.compare-row { display: grid; grid-template-columns: 1fr auto; gap: 14px; align-items: center; padding: 12px 0; border-bottom: 1px solid #e3e7e3; }
.compare-row:last-child { border-bottom: 0; }

.method-steps { counter-reset: method; display: grid; gap: 16px; }
.method-step { counter-increment: method; background: #fff; border: 1px solid var(--line); border-radius: 16px; padding: 23px 23px 23px 76px; position: relative; }
.method-step::before { content: counter(method); position: absolute; left: 22px; top: 21px; width: 37px; height: 37px; border-radius: 50%; display: grid; place-items: center; background: var(--deep); color: var(--lime); font-weight: 900; }
.method-step h2 { margin: 0 0 7px; font-size: 1.18rem; }
.method-step p { margin: 0; color: var(--muted); }

.cta-band { background: var(--copper); color: #fff; border-radius: var(--radius); padding: 32px; display: flex; justify-content: space-between; align-items: center; gap: 28px; }
.cta-band h2 { margin: 0; font-family: Georgia, serif; font-size: 2rem; font-weight: 500; }
.cta-band p { margin: 7px 0 0; color: #ffebe1; }

.site-footer { background: #0a211f; color: #c5d5d1; padding: 52px 0 20px; }
.footer-grid { display: grid; grid-template-columns: 1.4fr .8fr .8fr; gap: 42px; }
.footer-brand { color: #fff; font-family: Georgia, serif; font-size: 1.5rem; }
.site-footer p { max-width: 490px; }
.site-footer h2 { color: #fff; font-size: .85rem; text-transform: uppercase; letter-spacing: .1em; }
.site-footer a { display: block; color: #c5d5d1; text-decoration: none; margin: 7px 0; font-size: .9rem; }
.site-footer a:hover { color: #fff; text-decoration: underline; }
.footer-bottom { border-top: 1px solid rgba(255,255,255,.12); margin-top: 35px; padding-top: 17px; display: flex; justify-content: space-between; gap: 20px; font-size: .74rem; color: #94aaa5; }

@media (max-width: 980px) {
    .hero-grid, .content-grid, .audit-layout { grid-template-columns: 1fr; }
    .hero-panel { max-width: 680px; }
    .card-grid { grid-template-columns: repeat(2, 1fr); }
    .feature-grid { grid-template-columns: 1fr; }
    .sidebar, .audit-results { position: static; }
    .search-row { grid-template-columns: 1fr 210px; }
    .search-row .button { grid-column: 1 / -1; }
    .footer-grid { grid-template-columns: 1.2fr 1fr 1fr; }
}

@media (max-width: 760px) {
    body { font-size: 16px; }
    .site-header { position: relative; }
    .header-inner { min-height: 70px; }
    .brand small { display: none; }
    .nav-toggle { display: block; }
    .primary-nav { display: none; position: absolute; top: 70px; left: 0; right: 0; background: var(--deep); padding: 10px 16px 18px; flex-direction: column; align-items: stretch; border-top: 1px solid rgba(255,255,255,.1); }
    .primary-nav.open { display: flex; }
    .primary-nav a { padding: 12px; }
    .hero-grid { padding: 62px 0 70px; gap: 35px; }
    .hero h1 { font-size: clamp(2.7rem, 14vw, 4.1rem); }
    .section { padding: 56px 0; }
    .section-head { display: block; }
    .section-head p { margin-top: 12px; }
    .search-panel { margin-top: -25px; }
    .search-row, .compare-form { grid-template-columns: 1fr; }
    .compare-vs { padding: 0; text-align: center; }
    .card-grid, .trial-grid, .compare-grid, .split, .matrix, .footer-grid { grid-template-columns: 1fr; }
    .check-grid { grid-template-columns: 1fr; }
    .summary-grid { grid-template-columns: repeat(3, 1fr); }
    .page-hero { padding: 45px 0 50px; }
    .cta-band { display: block; }
    .cta-band .button { margin-top: 18px; }
    .footer-bottom { flex-direction: column; }
}

@media print {
    .site-header, .medical-banner, .site-footer, .nav-toggle, .button, .audit-picker { display: none !important; }
    body { background: #fff; color: #000; }
    .audit-layout { display: block; }
    .audit-results { position: static; }
    .finding, .audit-summary { break-inside: avoid; }
}

[hidden] { display: none !important; }
.feature-card { color: var(--ink); }
