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Measuring ageing

The tests, endpoints and research frameworks used to judge biological and functional change.

SchematicWhat does the measurement answer?

Collect a defined sampleRecord the population, tissue and observation time.
Apply the measurementThe assay or model has a stated target.
Compare with functionFollow the relevant outcome and its duration.

A predicted age and a measured functional outcome are different quantities.

Programmes in this field

Each dossier describes the mechanism, studies and development history of a research programme.

1 programme and 2 articles in this edition.

Programme records

MeasurementHuman study

XPRIZE Healthspan measurement and trials

XPRIZE Foundation and participating research teams

XPRIZE Healthspan organises a competition around improvements in muscle, cognitive and immune function. Twenty teams entered the finals in August 2026. Its contribution is a shared trial and measurement framework; finalist selection is not evidence that a competing intervention has achieved the prize's target.

HumansRead dossier

Research and explanations

Cell samples arranged beside a sculptural calibration instrument with nested plates.

Explainer4 min read

What a younger ageing-clock reading can tell us

An ageing clock converts biological measurements into a prediction. Its training target determines what that prediction means. A lower reading after an intervention still needs to be tested against lasting health outcomes.

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A figure walking on an assessment platform beside a tissue specimen with simplified cells.

Explainer4 min read

What would establish human rejuvenation?

A claim about human rejuvenation needs a defined change, a credible comparison and enough observation to establish benefit and harm. Tissue markers, functional outcomes and longer follow-up answer different questions.

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